Ryan told CVG in an E3 interview that the system's slate of games, fromThe Last of Us Remastered in July to Call of Duty: Advanced Warfareand Far Cry 4 in November, will have a powerful $#@!ulative effect on system sales.
"But if I had to pick one, it'd probably be Destiny," Ryan said. "We're partnered up with Activision on that. The intensity and depth that the two organisations are working at is something I've never seen before. Both really want to make this work in a really serious way.
"The game is obviously multiformat so it will be out on Xbox One and 360, as it will be on PS3. But I think, certainly in our eyes, the main prize is the PS4 version of the game. We want to make that absolutely enormous."
Sony plans to support Destiny with an exclusive white PS4 systembundled with the game at launch. PlayStation 3 and PlayStation 4 players will be the first to try Destiny's beta, which begins July 17.
Check out our hands-on E3 preview with Destiny for more on Bungie's online shooter.

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