This is Vanquish, a new game by Shinji Mikami, the creator of the Resident Evil series.
What you see in this clip is all we know about the game. There's an attack on the United States (aliens?), there's real actors in it, and you'll be playing some guy that looks like an albino Master Chief.
There's no word on which platform it's for (though it's shiny enough to assume 360/PS3), what it's like, nor who's developing it, or who's even publishing it: you'd think it would be Mikami's own company, Platinum Games, but since there's no mention of that, we can't be 100% sure.

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