Genesis Plus 1.4.1 released by EkeEke is an updated Genesis/Megadrive Emulator for Wii/Gamecube

Heres whats new:

Genesis Plus GX 1.4.1 (04/12/2010) (Eke-Eke)
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[Core/VDP]
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* improved VBLANK flag accuracy, as observed on real hardware.
* improved DMA operations accuracy, writes are now performed on a scanline basis: fixes Gaiares (flickering title screen).
* improved DMA Fill timing accuracy.
* fixed DMA with bad code values: fixes Williams Arcade Classics (corrupted gfx after soft reset).
* fixed horizontal resolution changes during HBLANK: fixes Bugs Bunny in Double Trouble (2nd stage).
* fixed Vertical Counter in interlace mode 1, as observed on real hardware.
* fixed horizontal border width, as observed on real hardware.
* various code improvments & optimizations.

[Core/Extra]
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* improved savestate format: added DMA, SVP, cartridge mapping & internal registers state informations
* improved unlicensed ROM mappers emulation
* added Chinese Fighters III mapper support
* added Top Fighter mapper support
* fixed Barver Battle Saga mapper support
* fixed cartridge hardware soft-reset (Game Genie, SVP, ...)
* fixed Game Genie registers byte reads

[Gamecube/Wii]
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* added message box when inputs config uses disconnected controllers.
* added message box when settings are reseted to default on startup.
* fixed default inputs configuration.
* fixed memory leak in Cheat Menu causing spurious resets.
* added an option to enable/disable automatic cheat activation
* increased max number of cheat codes
* optimized cheat codes requiring RAM patching.
* improved default horizontal scaling to better match output from a real Mega Drive

[Gamecube specific]
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* fixed inverted keys in cheat menu.
* fixed audio input frequency, now use exact audio hardware samplerate, as measured on my Game Cube (~48044 Hz),
(NB: Wii samplerate has been verified to be closer to 48000 Hz)

[Wii specific]
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* added the possibility for any wiimotes to be used as input device, regardless of the connected expansion controller.
* fixed USB drive not being detected when application is loaded from USB (HBC), thanks to Tantric for the tips.

http://code.google.com/p/genplus-gx/