This sounds bloody great news, i loved the PC Duke Nukem 3D games, heres the details:

Normmatt, developer of AKAIO, has recently disclosed to me that he is working on bringing the Duke back! Norm has obtained the source code for the now defunct Duke 3D NDS Homebrew port. The updated project has already been compiled with the latest DevKitARM and LibNDS, which means DSi-Mode support. After a brief discussion with Normmatt, I have learned that the project will probably include sound support, with plans for possible other enhancements as well. More information will be posted when it becomes available to us.

http://gbatemp.net/t284314-bring-back-the-duke