Super Mario Bros 3.
I have to give Magicland Dizzy a mention though, because after Mario, Dizzy is my favourite game series. I like the combination of the traditional adventure game with platforms and spent more time as a child playing Dizzy than any other games.
Other honorable mentions:
Spindizzy (not a part of the Dizzy series mentioned above, an amazing isometric 3D game)
Mario Kart DS (yes this is my favourite version, imo plays much better than the SNES version)
Chuckie Egg (doesnt get more simple than this but was one of the early platformers)
The majority of modern games do nothing for me.