News from SonnyJim:
Amadeus has managed to fix the C++ toolchain for DSLinux and is currently in the process of porting the PIXIL suite.
Screenshots - http://users.tamuk.edu/ksjas29/pixil.html
Calculator in portait mode - http://img234.imageshack.us/img234/372/dsc00678tj5.jpg
It's probably more than likely that this will require some kind of RAM in Slot-2.