Hm, this would definitely require some hardware modifications of some sort. I know there is a device that hooks a DS up to a TV, but it only does the top screen so it's not all that useful.
The main problem is the touchscreen, as it would be difficult to magnify that and still retain its ability to detect touches.
The closest thing I can think of would be the Jumbotron DS project, but the creator used nearly $600 worth of spare parts to make it.
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