via http://www.aep-emu.de/

M64Py is a Qt based front-end (GUI) for Mupen64Plus, a cross-platform plugin-based Nintendo 64 emulator.
The front-end is written in Python and it provides a user-friendly interface over Mupen64Plus shared library.

Quote:
Version 0.2.3

  • Migrated to Qt5
  • Python3 support
  • Toggle video extension without restart
  • Add windows portable build