You're not really hacking the DS by buying a CycloDS. It won't have any lasting effect on the DS, trust me.
GBA homebrew however cannot be run from slot-1 in any way, shape, or form. You MUST have a slot-2 device to run it. Most users get a slot-1 device like the CycloDS and a slot-2 expansion pack like the EZ-V 3in1 expansion pack. This lets them keep their GBA files on their slot-1 microSD card use software on the DS to transfer a single file to the expansion pack and run it.
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