I personally think Slot-2 devices are currently better, mainly because they can simply do more, i.e GBA games and more homebrew.
The Slot-1 device are simpler though, with no patching of games required, ad no Boot device needed.
I reckon the best will be to have both a Slot-1 and Slot-2 device (M3 Lite + M3 DS?) where the Slot-1 device can use the Slot-2 device for GBA compatibility and extra storage, but dosn't rely on the Slot-2 device for normal NDS homebrew and games. i'll keep my fingers crossed :-P
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