The Wii U version of Mass Effect 3 will not feature support for a 1080p resolution.
So confirmed Straight Right CEO Tom Crago, stomping on a Nintendo Power rumour claiming otherwise."The game will run at 720p," stated Crago, according to Official Nintendo Magazine.
Straight Right is the developer handling the Wii U port of the BioWare game, which publisher EA confirmed will be a launch game for the Nintendo console later this year.
BioWare's first ever title on a Nintendo home console will feature a new control scheme designed to incorporate the Wii U GamePad, as well as "bonus DLC including the Extended Cut, an interactive back story covering previous events in the Mass Effect universe, and Mass Effect 3′s critically acclaimed multiplayer experience".

http://www.computerandvideogames.com...-run-in-1080p/