Some News from our friends over at Emulation 64:

RxNES has returned with a new release now to 3.003, RxNES is a unity powered emulator based on MyNes, it allows enhancements and modifications, that allow replacements of tiles, with either 3D models, or sprites, regardless of size, has full custom scripting in c# which allows limitless possibilities for modding, and even allows the use of midi instruments.

You can download the current version here, and feel free to discuss here, and i'll try to answer any questions

http://www.emulation64.com/files/info/1527/

via http://www.emulation64.com/view/2832/RxNES-3/